Proteolytic activation of the cell death protease Yama/CPP32 by granzyme B.

The serine protease granzyme B, which is secreted by cytotoxic cells, is one of the major effectors of apoptosis in susceptible targets. To examine the apoptotic mechanism of granzyme B, we have analyzed its effect on purified proteins that are thought to be components of death pathways inherent to...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Quan, L T, Tewari, M, O'Rourke, K, Dixit, V, Snipas, S J, Poirier, G G, Ray, C, Pickup, D J, Salvesen, G S
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39893/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8700869/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.5.1972
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