Studies of the lamin proteinase reveal multiple parallel biochemical pathways during apoptotic execution.

Although specific proteinases play a critical role in the active phase of apoptosis, their substrates are largely unknown. We previously identified poly(ADP-ribose) polymerase (PARP) as an apoptosis-associated substrate for proteinase(s) related to interleukin 1 beta-converting enzyme (ICE). Now we...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Lazebnik, Y A, Takahashi, A, Moir, R D, Goldman, R D, Poirier, G G, Kaufmann, S H, Earnshaw, W C
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC40920/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7568069/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.20.9042
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