Studies of the lamin proteinase reveal multiple parallel biochemical pathways during apoptotic execution.

Although specific proteinases play a critical role in the active phase of apoptosis, their substrates are largely unknown. We previously identified poly(ADP-ribose) polymerase (PARP) as an apoptosis-associated substrate for proteinase(s) related to interleukin 1 beta-converting enzyme (ICE). Now we...

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Bibliographic Details
Main Authors: Lazebnik, Y A, Takahashi, A, Moir, R D, Goldman, R D, Poirier, G G, Kaufmann, S H, Earnshaw, W C
Format: Artigo
Language:Inglês
Published: 1995
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC40920/
https://ncbi.nlm.nih.gov/pubmed/7568069
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