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Disruption of Nuclear Lamin Organization Blocks the Elongation Phase of DNA Replication

The role of nuclear lamins in DNA replication is unclear. To address this, nuclei were assembled in Xenopus extracts containing AraC, a reversible inhibitor that blocks near the onset of the elongation phase of replication. Dominant-negative lamin mutants lacking their NH(2)-terminal domains were ad...

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Bibliografski detalji
Glavni autori: Moir, Robert D., Spann, Timothy P., Herrmann, Harald, Goldman, Robert D.
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2000
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2175110/
https://ncbi.nlm.nih.gov/pubmed/10851016
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