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Functions and dysfunctions of the nuclear lamin Ig-fold domain in nuclear assembly, growth, and Emery–Dreifuss muscular dystrophy

The non-α-helical C terminus of Xenopus lamin B3 (LB3T) inhibits the polymerization of lamin B3 in vitro and prevents the assembly of nuclei in Xenopus egg interphase extracts. To more precisely define the functions of LB3T in nuclear assembly, we have expressed subdomains of LB3T and determined the...

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Bibliografski detalji
Glavni autori: Shumaker, Dale K., Lopez-Soler, Reynold I., Adam, Stephen A., Herrmann, Harald, Moir, Robert D., Spann, Timothy P., Goldman, Robert D.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2005
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1255737/
https://ncbi.nlm.nih.gov/pubmed/16227433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0507612102
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