Á lódáil...

S1PR1 is crucial for accumulation of regulatory T cells in tumors via STAT3

S1PR1 signaling has been shown to restrain the number and function of Tregs in the periphery under physiological conditions and in colitis models, but its role in regulating tumor-associated T cells is unknown. Here, we show that S1PR1 signaling in T cells drives Treg accumulation in tumors, limits...

Cur síos iomlán

Na minha lista:
Sonraí Bibleagrafaíochta
Main Authors: Priceman, Saul J., Shen, Shudan, Wang, Lin, Deng, Jiehui, Yue, Chanyu, Kujawski, Maciej, Yu, Hua
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3988983/
https://ncbi.nlm.nih.gov/pubmed/24630990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.02.016
Clibeanna: Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!