Regulation of adipose tissue T cell subsets by Stat3 is crucial for diet-induced obesity and insulin resistance

Dysregulated inflammation in adipose tissue, marked by increased proinflammatory T-cell accumulation and reduced regulatory T cells (Tregs), contributes to obesity-associated insulin resistance. The molecular mechanisms underlying T-cell-mediated inflammation in adipose tissue remain largely unknown...

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Bibliographic Details
Main Authors: Priceman, Saul J., Kujawski, Maciej, Shen, Shudan, Cherryholmes, Gregory A., Lee, Heehyoung, Zhang, Chunyan, Kruper, Laura, Mortimer, Joanne, Jove, Richard, Riggs, Arthur D., Yu, Hua
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2013
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3740863/
https://ncbi.nlm.nih.gov/pubmed/23878227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1311557110
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