Impaired 8-Hydroxyguanine Repair Activity of MUTYH Variant p.Arg109Trp Found in a Japanese Patient with Early-Onset Colorectal Cancer

Purpose. The biallelic inactivation of the 8-hydroxyguanine repair gene MUTYH leads to MUTYH-associated polyposis (MAP), which is characterized by colorectal multiple polyps and carcinoma(s). However, only limited information regarding MAP in the Japanese population is presently available. Since ear...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Shinmura, Kazuya, Goto, Masanori, Tao, Hong, Kato, Hisami, Suzuki, Rie, Nakamura, Satoki, Matsuda, Tomonari, Yin, Guang, Morita, Makiko, Kono, Suminori, Sugimura, Haruhiko
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3988950/
https://ncbi.nlm.nih.gov/pubmed/24799981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/617351
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars