BAF180 Promotes Cohesion and Prevents Genome Instability and Aneuploidy

BAF180, a subunit of the PBAF chromatin remodeling complex, is frequently mutated in cancer. Although PBAF regulates transcription, it remains unclear whether this is what drives tumorigenesis in cells lacking BAF180. Based on data from yeast, we hypothesized that BAF180 may prevent tumorigenesis by...

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Detaylı Bibliyografya
Asıl Yazarlar: Brownlee, Peter M., Chambers, Anna L., Cloney, Ross, Bianchi, Alessandro, Downs, Jessica A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cell Press 2014
Konular:
Report
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3988838/
https://ncbi.nlm.nih.gov/pubmed/24613357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.02.012
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