Sonic Hedgehog Signaling Drives Proliferation of Synoviocytes in Rheumatoid Arthritis: A Possible Novel Therapeutic Target

Sonic hedgehog (Shh) signaling controls many aspects of human development, regulates cell growth and differentiation in adult tissues, and is activated in a number of malignancies. Rheumatoid arthritis (RA) is characterized by chronic synovitis and pannus formation associated with activation of fibr...

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Bibliographic Details
Main Authors: Wang, Mingxia, Zhu, Shangling, Peng, Weixiang, Li, Qiuxia, Li, Zhaoxia, Luo, Minqi, Feng, Xiaoxue, Lin, Zhuofeng, Huang, Jianlin
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3987882/
https://ncbi.nlm.nih.gov/pubmed/24741597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/401903
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