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Receptor Tyrosine Kinases Fall into Distinct Classes Based on Their Inferred Signaling Networks
Although many anticancer drugs that target receptor tyrosine kinases (RTKs) provide clinical benefit, their long-term use is limited by resistance that is often attributed to increased abundance or activation of another RTK that compensates for the inhibited receptor. To uncover common and unique fe...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3987808/ https://ncbi.nlm.nih.gov/pubmed/23861540 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2003994 |
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