लोड हो रहा है...
Integrated Mimicry of B Cell Antibody Mutagenesis Using Yeast Homologous Recombination
Antibody affinity maturation proceeds in vivo via a combination of point mutations, insertions, deletions, and combinatorial shuffling of light chains or portions of the heavy chain, thereby reducing the probability of trapping in local affinity optima in sequence space. In vivo homologous recombina...
में बचाया:
| मुख्य लेखकों: | , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2011
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3986863/ https://ncbi.nlm.nih.gov/pubmed/20645027 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12033-010-9312-3 |
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