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MHC class I-presented peptides and the DRiP hypothesis
MHC class I molecules present peptides derived from intracellular proteins, enabling immune surveillance by CD8+ T cells and the elimination of virally infected and cancerous cells. It has been argued that the dominant source of MHC class I-presented peptides is through proteasomal degradation of ne...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3986829/ https://ncbi.nlm.nih.gov/pubmed/24566257 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.it.2014.01.002 |
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