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The Specificity of Trimming of MHC Class I-Presented Peptides in the Endoplasmic Reticulum
Aminopeptidases in the endoplasmic reticulum (ER) can cleave antigenic peptides and in so doing either create or destroy MHC class I-presented epitopes. However the specificity of this trimming process overall and of the major ER aminopeptidase ERAP1 in particular is not well understood. This issue...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2855122/ https://ncbi.nlm.nih.gov/pubmed/19828632 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0803663 |
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