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Using intein catalysis to probe the origin of major histocompatibility complex class I-presented peptides
All vertebrate nucleated cells generate peptides from their expressed gene products and then display them at the cell surface bound to MHC class I molecules. This allows CD8(+) T cells to detect and eliminate abnormal cells that are synthesizing foreign proteins, e.g., from viruses or mutations. To...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3479494/ https://ncbi.nlm.nih.gov/pubmed/23027972 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1210271109 |
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