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Atrial Fibrillation-Linked Germline GJA5/Connexin40 Mutants Showed an Increased Hemichannel Function

Mutations in GJA5 encoding the gap junction protein connexin40 (Cx40) have been linked to lone atrial fibrillation. Some of these mutants result in impaired gap junction function due to either abnormal connexin localization or impaired gap junction channels, which may play a role in promoting atrial...

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Bibliografiske detaljer
Main Authors: Sun, Yiguo, Hills, Matthew D., Ye, Willy G., Tong, Xiaoling, Bai, Donglin
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3986259/
https://ncbi.nlm.nih.gov/pubmed/24733048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0095125
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