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In vivo radiation response of proneural glioma characterized by protective p53 transcriptional program and proneural-mesenchymal shift

Glioblastoma is the most common adult primary brain tumor and has a dismal median survival. Radiation is a mainstay of treatment and significantly improves survival, yet recurrence is nearly inevitable. Better understanding the radiation response of glioblastoma will help improve strategies to treat...

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Detalhes bibliográficos
Main Authors: Halliday, John, Helmy, Karim, Pattwell, Siobhan S., Pitter, Kenneth L., LaPlant, Quincey, Ozawa, Tatsuya, Holland, Eric C.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3986190/
https://ncbi.nlm.nih.gov/pubmed/24706837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1321014111
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