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Genome sequencing of disease and carriage isolates of nontypeable Haemophilus influenzae identifies discrete population structure

One of the main hurdles for the development of an effective and broadly protective vaccine against nonencapsulated isolates of Haemophilus influenzae (NTHi) lies in the genetic diversity of the species, which renders extremely difficult the identification of cross-protective candidate antigens. To a...

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Autors principals: De Chiara, Matteo, Hood, Derek, Muzzi, Alessandro, Pickard, Derek J., Perkins, Tim, Pizza, Mariagrazia, Dougan, Gordon, Rappuoli, Rino, Moxon, E. Richard, Soriani, Marco, Donati, Claudio
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3986186/
https://ncbi.nlm.nih.gov/pubmed/24706866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1403353111
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