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Absence of an Important Vaccine and Diagnostic Target in Carriage- and Disease-Related Nontypeable Haemophilus influenzae

Nontypeable Haemophilus influenzae (NTHi)-associated disease is a major health problem globally. Whole-genome sequence analysis identified the absence of hpd genes encoding Haemophilus protein D in 3 of 16 phylogenetically distinct NTHi isolates. This novel finding is of potential clinical significa...

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Detalhes bibliográficos
Main Authors: Smith-Vaughan, Heidi C., Chang, Anne B., Sarovich, Derek S., Marsh, Robyn L., Grimwood, Keith, Leach, Amanda J., Morris, Peter S., Price, Erin P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3910944/
https://ncbi.nlm.nih.gov/pubmed/24285816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00632-13
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