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Genome sequencing of disease and carriage isolates of nontypeable Haemophilus influenzae identifies discrete population structure

One of the main hurdles for the development of an effective and broadly protective vaccine against nonencapsulated isolates of Haemophilus influenzae (NTHi) lies in the genetic diversity of the species, which renders extremely difficult the identification of cross-protective candidate antigens. To a...

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Detalhes bibliográficos
Main Authors: De Chiara, Matteo, Hood, Derek, Muzzi, Alessandro, Pickard, Derek J., Perkins, Tim, Pizza, Mariagrazia, Dougan, Gordon, Rappuoli, Rino, Moxon, E. Richard, Soriani, Marco, Donati, Claudio
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3986186/
https://ncbi.nlm.nih.gov/pubmed/24706866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1403353111
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