Genome sequencing of disease and carriage isolates of nontypeable Haemophilus influenzae identifies discrete population structure

One of the main hurdles for the development of an effective and broadly protective vaccine against nonencapsulated isolates of Haemophilus influenzae (NTHi) lies in the genetic diversity of the species, which renders extremely difficult the identification of cross-protective candidate antigens. To a...

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Bibliografiska uppgifter
Huvudupphovsmän: De Chiara, Matteo, Hood, Derek, Muzzi, Alessandro, Pickard, Derek J., Perkins, Tim, Pizza, Mariagrazia, Dougan, Gordon, Rappuoli, Rino, Moxon, E. Richard, Soriani, Marco, Donati, Claudio
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2014
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3986186/
https://ncbi.nlm.nih.gov/pubmed/24706866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1403353111
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