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Observation of Complete Pressure-Jump Protein Refolding in Molecular Dynamics Simulation and Experiment

[Image: see text] Density is an easily adjusted variable in molecular dynamics (MD) simulations. Thus, pressure-jump (P-jump)-induced protein refolding, if it could be made fast enough, would be ideally suited for comparison with MD. Although pressure denaturation perturbs secondary structure less t...

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Detalhes bibliográficos
Main Authors: Liu, Yanxin, Prigozhin, Maxim B., Schulten, Klaus, Gruebele, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3985862/
https://ncbi.nlm.nih.gov/pubmed/24437525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja412639u
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