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Structural Characterization of λ-Repressor Folding from All-Atom Molecular Dynamics Simulations

The five-helix bundle λ-repressor fragment is a fast-folding protein. A length of 80 amino acid residues puts it on the large end among all known microsecond folders and its size poses a computational challenge for molecular dynamics (MD) studies. We simulated the folding of a novel λ-repressor fast...

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Bibliographic Details
Main Authors: Liu, Yanxin, Strümpfer, Johan, Freddolino, Peter L., Gruebele, Martin, Schulten, Klaus
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3377354/
https://ncbi.nlm.nih.gov/pubmed/22737279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jz300017c
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