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Comparing Fast Pressure Jump and Temperature Jump Protein Folding Experiments and Simulations

The unimolecular folding reaction of small proteins is now amenable to a very direct mechanistic comparison between experiment and simulation. We present such a comparison of microsecond pressure and temperature jump refolding kinetics of the engineered WW domain FiP35, a model system for beta sheet...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Wirth, Anna Jean, Liu, Yanxin, Prigozhin, Maxim B., Schulten, Klaus, Gruebele, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4794261/
https://ncbi.nlm.nih.gov/pubmed/25988868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b02474
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