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Colloidal Drug Formulations Can Explain “Bell-Shaped” Concentration–Response Curves
[Image: see text] Drug efficacy does not always increase sigmoidally with concentration, which has puzzled the community for decades. Unlike standard sigmoidal curves, bell-shaped concentration–response curves suggest more complex biological effects, such as multiple-binding sites or multiple target...
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| Hoofdauteurs: | , , , , , , |
|---|---|
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American
Chemical
Society
2014
|
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3985758/ https://ncbi.nlm.nih.gov/pubmed/24397822 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb4007584 |
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