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Two Regions of the Ryanodine Receptor Calcium Channel Are Involved in Ca(2+)-Dependent Inactivation

[Image: see text] Skeletal (RyR1) and cardiac muscle (RyR2) isoforms of ryanodine receptor calcium channels are inhibited by millimollar Ca(2+), but the affinity of RyR2 for inhibitory Ca(2+) is ∼10 times lower than that of RyR1. Previous studies demonstrated that the C-terminal quarter of RyR has c...

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Detalhes bibliográficos
Main Authors: Gomez, Angela C., Yamaguchi, Naohiro
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3985739/
https://ncbi.nlm.nih.gov/pubmed/24521037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi401586h
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