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Structural Regions of the Cardiac Ca Channel α(1C) Subunit Involved in Ca-dependent Inactivation

We investigated the molecular basis for Ca-dependent inactivation of the cardiac L-type Ca channel. Transfection of HEK293 cells with the wild-type α(1C) or its 3′ deletion mutant (α(1C−3′del)) produced channels that exhibited prominent Ca-dependent inactivation. To identify structural regions of α(...

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Detalhes bibliográficos
Main Authors: Adams, Brett, Tanabe, Tsutomu
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2229381/
https://ncbi.nlm.nih.gov/pubmed/9379170
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