A TET Homologue Protein from Coprinopsis cinerea (CcTET) That Biochemically Converts 5-Methylcytosine to 5-Hydroxymethylcytosine, 5-Formylcytosine, and 5-Carboxylcytosine

[Image: see text] DNA methylation (5-methylcytosine, 5mC) plays critical biological functions in mammals and plants as a vital epigenetic marker. The Ten-Eleven translocation dioxygenases (TET1, 2, and 3) have been found to oxidize 5mC to 5-hydroxymethylcytosine (5hmC) and then to 5-formylcytosine (...

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Bibliographic Details
Main Authors: Zhang, Liang, Chen, Weizhong, Iyer, Lakshminarayan M., Hu, Jennifer, Wang, Gloria, Fu, Ye, Yu, Miao, Dai, Qing, Aravind, L., He, Chuan
Format: Artigo
Language:Inglês
Published: American Chemical Society 2014
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3985729/
https://ncbi.nlm.nih.gov/pubmed/24655109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja500979k
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