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A TET Homologue Protein from Coprinopsis cinerea (CcTET) That Biochemically Converts 5-Methylcytosine to 5-Hydroxymethylcytosine, 5-Formylcytosine, and 5-Carboxylcytosine
[Image: see text] DNA methylation (5-methylcytosine, 5mC) plays critical biological functions in mammals and plants as a vital epigenetic marker. The Ten-Eleven translocation dioxygenases (TET1, 2, and 3) have been found to oxidize 5mC to 5-hydroxymethylcytosine (5hmC) and then to 5-formylcytosine (...
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Main Authors: | , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Chemical
Society
2014
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3985729/ https://ncbi.nlm.nih.gov/pubmed/24655109 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja500979k |
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