Direct activation of human and mouse Oct4 genes using engineered TALE and Cas9 transcription factors

The newly developed transcription activator-like effector protein (TALE) and clustered regularly interspaced short palindromic repeats/Cas9 transcription factors (TF) offered a powerful and precise approach for modulating gene expression. In this article, we systematically investigated the potential...

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Bibliografiska uppgifter
Huvudupphovsmän: Hu, Jiabiao, Lei, Yong, Wong, Wing-Ki, Liu, Senquan, Lee, Kai-Chuen, He, Xiangjun, You, Wenxing, Zhou, Rui, Guo, Jun-Tao, Chen, Xiongfong, Peng, Xianlu, Sun, Hao, Huang, He, Zhao, Hui, Feng, Bo
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2014
Ämnen:
Gene Regulation, Chromatin and Epigenetics
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3985678/
https://ncbi.nlm.nih.gov/pubmed/24500196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku109
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