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Neurodegeneration-associated instability of ribosomal DNA

Homologous recombination (HR)-mediated instability of the repetitively organized ribosomal DNA (rDNA) has been proposed as a mediator of cell senescence in yeast triggering the DNA damage response. High individual variability in the content of human rDNA suggests that this genomic region remained re...

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Detalles Bibliográficos
Main Authors: Hallgren, Justin, Pietrzak, Maciej, Rempala, Grzegorz, Nelson, Peter T., Hetman, Michal
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3985612/
https://ncbi.nlm.nih.gov/pubmed/24389328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2013.12.012
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