Requirement of Neuronal Ribosome Synthesis for Growth and Maintenance of the Dendritic Tree

The nucleolus serves as a principal site of ribosome biogenesis but is also implicated in various non-ribosomal functions, including negative regulation of the pro-apoptotic transcription factor p53. Although disruption of the nucleolus may trigger the p53-dependent neuronal death, neurotoxic conseq...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Slomnicki, Lukasz P., Pietrzak, Maciej, Vashishta, Aruna, Jones, James, Lynch, Nicholas, Elliot, Shane, Poulos, Eric, Malicote, David, Morris, Bridgit E., Hallgren, Justin, Hetman, Michal
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Neurobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4786710/
https://ncbi.nlm.nih.gov/pubmed/26757818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.682161
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