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Calcium Inhibition of Ribonuclease H1 Two-Metal Ion Catalysis
[Image: see text] Most phosphate-processing enzymes require Mg(2+) as a cofactor to catalyze nucleotide cleavage and transfer reactions. Ca(2+) ions inhibit many of these enzymatic activities, despite Ca(2+) and Mg(2+) having comparable binding affinities and overall biological abundances. Here we s...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Chemical
Society
2014
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3985467/ https://ncbi.nlm.nih.gov/pubmed/24499076 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja411408x |
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