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The pH-dependent configurations of a 5-Chlorouracil-Guanine Base Pair

Hypochlorous acid (HOCl) from activated neutrophils at sites of inflammation can react with and damage biological molecules including nucleic acids. The reaction of HOCl with cytosine analogs can generate multiple products including 5-chlorouracil (ClU). In this paper, we have constructed oligonucle...

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Detalhes bibliográficos
Main Authors: Theruvathu, Jacob A., Kim, Cherine H., Darwanto, Agus, Neidigh, Jonathan W., Sowers, Lawrence C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3985288/
https://ncbi.nlm.nih.gov/pubmed/19863157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi901154t
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