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The pH-dependent configurations of a 5-Chlorouracil-Guanine Base Pair

Hypochlorous acid (HOCl) from activated neutrophils at sites of inflammation can react with and damage biological molecules including nucleic acids. The reaction of HOCl with cytosine analogs can generate multiple products including 5-chlorouracil (ClU). In this paper, we have constructed oligonucle...

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Autori principali: Theruvathu, Jacob A., Kim, Cherine H., Darwanto, Agus, Neidigh, Jonathan W., Sowers, Lawrence C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3985288/
https://ncbi.nlm.nih.gov/pubmed/19863157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi901154t
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