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The pH-dependent configurations of a 5-Chlorouracil-Guanine Base Pair

Hypochlorous acid (HOCl) from activated neutrophils at sites of inflammation can react with and damage biological molecules including nucleic acids. The reaction of HOCl with cytosine analogs can generate multiple products including 5-chlorouracil (ClU). In this paper, we have constructed oligonucle...

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書誌詳細
主要な著者: Theruvathu, Jacob A., Kim, Cherine H., Darwanto, Agus, Neidigh, Jonathan W., Sowers, Lawrence C.
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3985288/
https://ncbi.nlm.nih.gov/pubmed/19863157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi901154t
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