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The pH-dependent configurations of a 5-Chlorouracil-Guanine Base Pair

Hypochlorous acid (HOCl) from activated neutrophils at sites of inflammation can react with and damage biological molecules including nucleic acids. The reaction of HOCl with cytosine analogs can generate multiple products including 5-chlorouracil (ClU). In this paper, we have constructed oligonucle...

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Библиографические подробности
Главные авторы: Theruvathu, Jacob A., Kim, Cherine H., Darwanto, Agus, Neidigh, Jonathan W., Sowers, Lawrence C.
Формат: Artigo
Язык:Inglês
Опубликовано: 2009
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3985288/
https://ncbi.nlm.nih.gov/pubmed/19863157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi901154t
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