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Prickle1 stunts limb growth through alteration of cell polarity and gene expression
BACKGROUND: Wnt/PCP signaling plays a critical role in multiple developmental processes, including limb development. Wnt5a, a ligand of the PCP pathway, signals through the Ror2/Vangl2 or the Vangl2/Ryk complex to regulate limb development along the proximal-distal axis in mice. Based on the interac...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3985166/ https://ncbi.nlm.nih.gov/pubmed/23913870 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.24025 |
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