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Analysis of PRICKLE1 in human cleft palate and mouse development demonstrates rare and common variants involved in human malformations
Palate development is shaped by multiple molecular signaling pathways, including the Wnt pathway. In mice and humans, mutations in both the canonical and noncanonical arms of the Wnt pathway manifest as cleft palate, one of the most common human birth defects. Like the palate, numerous studies also...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Wiley Periodicals, Inc.
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3960056/ https://ncbi.nlm.nih.gov/pubmed/24689077 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mgg3.53 |
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