Stress gates neural activation of BDNF in the mesolimbic reward pathway

BDNF, acting in the mesolimbic dopamine reward pathway, promotes susceptibility to stress; however, the mechanisms controlling its release remain unknown. We report that phasic optogenetic activation of this pathway increases BDNF levels in nucleus accumbens (NAc) of socially stressed mice, but not...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Walsh, Jessica J., Friedman, Allyson K., Sun, Haosheng, Heller, Elizabeth A., Ku, Stacy M., Juarez, Barbara, Burnham, Veronica L., Mazei-Robison, Michelle S., Ferguson, Deveroux, Golden, Sam A., Koo, Ja Wook, Chaudhury, Dipesh, Christoffel, Daniel J., Pomeranz, Lisa, Friedman, Jeffrey M., Russo, Scott J., Nestler, Eric J., Han, Ming-Hu
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3984932/
https://ncbi.nlm.nih.gov/pubmed/24270188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.3591
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky