BDNF is a Negative Modulator of Morphine Action

Brain-derived neurotrophic factor (BDNF) is a key positive regulator of neural plasticity, promoting for example, the actions of stimulant drugs of abuse such as cocaine. We discovered a surprising opposite role for BDNF in countering responses to chronic morphine. The suppression of BDNF in the ven...

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Main Authors: Koo, Ja Wook, Mazei-Robison, Michelle S., Chaudhury, Dipesh, Juarez, Barbara, LaPlant, Quincey, Ferguson, Deveroux, Feng, Jian, Sun, Haosheng, Scobie, Kimberly N., Damez-Werno, Diane, Crumiller, Marshall, Ohnishi, Yoshinori N., Ohnishi, Yoko H., Mouzon, Ezekiell, Dietz, David M., Lobo, Mary Kay, Neve, Rachael L., Russo, Scott J., Han, Ming-Hu, Nestler, Eric J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2012
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3547365/
https://ncbi.nlm.nih.gov/pubmed/23042896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1222265
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