Silencing the double-stranded RNA binding protein DGCR8 inhibits ovarian cancer cell proliferation, migration and invasion

PURPOSE: To evaluate the role of DiGeorge Critical Region 8 (DGCR8), a key component of miRNA biogenesis pathway in ovarian cancer. METHODS: The expression of DGCR8 in ovarian cancer was detected by immunostaining and DGCR8 knockdown in ovarian cancer cells was achieved using lentiviral shRNA. Diffe...

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Detalhes bibliográficos
Main Authors: Guo, Yuqi, Tian, Peng, Yang, Chuanhe, Liang, Zhibing, Li, Min, Sims, Michelle, Lu, Lu, Zhang, Zhan, Li, Hongwei, Pfeffer, Lawrence M., Yue, Junming
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3984613/
https://ncbi.nlm.nih.gov/pubmed/25823356
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