DiGeorge Syndrome Critical Region 8 (DGCR8) Protein-mediated microRNA Biogenesis Is Essential for Vascular Smooth Muscle Cell Development in Mice

DiGeorge Critical Region 8 (DGCR8) is a double-stranded RNA-binding protein that interacts with Drosha and facilitates microRNA (miRNA) maturation. However, the role of DGCR8 in vascular smooth muscle cells (VSMCs) is not well understood. To investigate whether DGCR8 contributes to miRNA maturation...

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Detalhes bibliográficos
Main Authors: Chen, Zixuan, Wu, Jianmin, Yang, Chuanhe, Fan, Pei, Balazs, Louisa, Jiao, Yan, Lu, Meifeng, Gu, Weikuan, Li, Chengyao, Pfeffer, Lawrence M., Tigyi, Gabor, Yue, Junming
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365935/
https://ncbi.nlm.nih.gov/pubmed/22511778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.351791
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