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Conditional deletion of Dicer in vascular smooth muscle cells leads to the developmental delay and embryonic mortality

Dicer is a RNAase III enzyme that cleaves double stranded RNA and generates small interfering RNA (siRNA) and microRNA (miRNA). The goal of this study is to examine the role of Dicer and miRNAs in vascular smooth muscle cells (VSMCs). We deleted Dicer in VSMCs of mice, which caused a developmental d...

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Bibliografiske detaljer
Main Authors: Pan, Yaoqian, Balazs, Louisa, Tigyi, Gabor, Yue, Junming
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3595544/
https://ncbi.nlm.nih.gov/pubmed/21371421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2011.02.119
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