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Conditional deletion of Dicer in vascular smooth muscle cells leads to the developmental delay and embryonic mortality
Dicer is a RNAase III enzyme that cleaves double stranded RNA and generates small interfering RNA (siRNA) and microRNA (miRNA). The goal of this study is to examine the role of Dicer and miRNAs in vascular smooth muscle cells (VSMCs). We deleted Dicer in VSMCs of mice, which caused a developmental d...
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| Główni autorzy: | , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2011
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3595544/ https://ncbi.nlm.nih.gov/pubmed/21371421 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2011.02.119 |
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