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Conditional deletion of Dicer in vascular smooth muscle cells leads to the developmental delay and embryonic mortality
Dicer is a RNAase III enzyme that cleaves double stranded RNA and generates small interfering RNA (siRNA) and microRNA (miRNA). The goal of this study is to examine the role of Dicer and miRNAs in vascular smooth muscle cells (VSMCs). We deleted Dicer in VSMCs of mice, which caused a developmental d...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3595544/ https://ncbi.nlm.nih.gov/pubmed/21371421 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2011.02.119 |
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