DiGeorge Syndrome Critical Region 8 (DGCR8) Protein-mediated microRNA Biogenesis Is Essential for Vascular Smooth Muscle Cell Development in Mice

DiGeorge Critical Region 8 (DGCR8) is a double-stranded RNA-binding protein that interacts with Drosha and facilitates microRNA (miRNA) maturation. However, the role of DGCR8 in vascular smooth muscle cells (VSMCs) is not well understood. To investigate whether DGCR8 contributes to miRNA maturation...

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Bibliographic Details
Main Authors: Chen, Zixuan, Wu, Jianmin, Yang, Chuanhe, Fan, Pei, Balazs, Louisa, Jiao, Yan, Lu, Meifeng, Gu, Weikuan, Li, Chengyao, Pfeffer, Lawrence M., Tigyi, Gabor, Yue, Junming
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2012
Subjects:
Developmental Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365935/
https://ncbi.nlm.nih.gov/pubmed/22511778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.351791
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