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DGCR8 Acts as an Adaptor for the Exosome Complex to Degrade Double-Stranded Structured RNAs

The Microprocessor complex (DGCR8/Drosha) is required for microRNA (miRNA) biogenesis but also binds and regulates the stability of several types of cellular RNAs. Of particular interest, DGCR8 controls the stability of mature small nucleolar RNA (snoRNA) transcripts independently of Drosha, suggest...

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Bibliografski detalji
Izdano u:Mol Cell
Glavni autori: Macias, Sara, Cordiner, Ross A., Gautier, Philippe, Plass, Mireya, Cáceres, Javier F.
Format: Artigo
Jezik:Inglês
Izdano: Cell Press 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4691244/
https://ncbi.nlm.nih.gov/pubmed/26687677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.11.011
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