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Similar behaviour of single-strand and double-strand siRNAs suggests they act through a common RNAi pathway

RNA interference (RNAi), mediated by either long double-stranded RNA (dsRNA) or short interfering RNA (siRNA), has become a routine tool for transient knockdown of gene expression in a wide range of organisms. The antisense strand of the siRNA duplex (antisense siRNA) was recently shown to have subs...

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Bibliografiske detaljer
Main Authors: Holen, Torgeir, Amarzguioui, Mohammed, Babaie, Eshrat, Prydz, Hans
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC154224/
https://ncbi.nlm.nih.gov/pubmed/12711685
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