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Comparative reactivity of human IgE to cynomolgus monkey and human effector cells and effects on IgE effector cell potency
Background: Due to genetic similarities with humans, primates of the macaque genus such as the cynomolgus monkey are often chosen as models for toxicology studies of antibody therapies. IgE therapeutics in development depend upon engagement with the FcεRI and FcεRII receptors on immune effector cell...
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| 主要な著者: | , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Landes Bioscience
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3984339/ https://ncbi.nlm.nih.gov/pubmed/24492303 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.27828 |
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