Llwytho...

In vivo transcriptional governance of hair follicle stem cells by canonical Wnt regulators

Hair follicle stem cells (HFSCs) regenerate hair in response to Wnt signalling. Here, we unfold genome-wide transcriptional and chromatin landscapes of β-catenin–TCF3/4–TLE circuitry, and genetically dissect their biological roles within the native HFSC niche. We show that during HFSC quiescence, TC...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Lien, Wen-Hui, Polak, Lisa, Lin, Mingyan, Lay, Kenneth, Zheng, Deyou, Fuchs, Elaine
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3984009/
https://ncbi.nlm.nih.gov/pubmed/24463605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2903
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!