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FOXC1 maintains the hair follicle stem cell niche and governs stem cell quiescence to preserve long-term tissue-regenerating potential

Adult tissue stem cells (SCs) reside in niches, which orchestrate SC behavior. SCs are typically used sparingly and exist in quiescence unless activated for tissue growth. Whether parsimonious SC use is essential to conserve long-term tissue-regenerating potential during normal homeostasis remains p...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Lay, Kenneth, Kume, Tsutomu, Fuchs, Elaine
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4801248/
https://ncbi.nlm.nih.gov/pubmed/26912458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1601569113
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