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Nfatc1 orchestrates aging in hair follicle stem cells

Hair production is fueled by stem cells (SCs), which transition between cyclical bouts of rest and activity. Here, we explore why hair growth wanes with age. We show that aged hair follicle SCs (HFSCs) in mice exhibit enhanced resting and abbreviated growth phases and are delayed in response to tiss...

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Detalhes bibliográficos
Main Authors: Keyes, Brice E., Segal, Jeremy P., Heller, Evan, Lien, Wen-Hui, Chang, Chiung-Ying, Guo, Xingyi, Oristian, Dan S., Zheng, Deyou, Fuchs, Elaine
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3870727/
https://ncbi.nlm.nih.gov/pubmed/24282298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1320301110
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