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In vivo transcriptional governance of hair follicle stem cells by canonical Wnt regulators
Hair follicle stem cells (HFSCs) regenerate hair in response to Wnt signalling. Here, we unfold genome-wide transcriptional and chromatin landscapes of β-catenin–TCF3/4–TLE circuitry, and genetically dissect their biological roles within the native HFSC niche. We show that during HFSC quiescence, TC...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3984009/ https://ncbi.nlm.nih.gov/pubmed/24463605 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2903 |
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